Now bear in mind that the Mac version has several compatibility issues as compared to its Windows counterpart. In case you want the native Ps2 Emulator for the Mac version, visit their download page. Wine is an compatibility layer(read emulator) that can run Windows applications on Linux, Mac, and BSD. There are two ways to go about it, the Mac version, and Wine. How to run PCSX2 on Macįactually speaking, the Mac port is not the best, given Apple’s issues with OpenGL APIs. PS3, Logitech, Xbox, you name it and chances are PCSX2 supports it as a controller. Top it off with wide compatibility of console controllers and you have the whole package.